Research
Daily Field Notes on emerging psychedelic clinical trials and pharmacology — N,N-DMT, 5-MeO-DMT, ayahuasca, ibogaine, and related tryptamines. Coverage of preprints, peer-reviewed papers from PubMed, and the major research centres (Imperial, MAPS, Beckley, Cybin, Usona). Receptor pharmacology, biased agonism, deuterated analogues, and the translation of psychedelic compounds from bench to clinic. Independent, evidence-led, primary sources cited.
DMT for Substance Misuse: An Exeter/Imperial Meta-Analysis
A systematic review and meta-analysis examining whether DMT-based interventions can shift the needle on substance misuse has appeared in the Journal of Psychopharmacology, authored by a team spanning the University of Exeter and Imperial College London
SPL028 Cybin 2024
What a careful read of the SPL028 Phase 1 synopsis tells us about deuteration....