Applied Research Through DMT

Altered Reality · Autonoetic Reflection

Daily Field Notes on emerging psychedelic research, plus long-form essays on pharmacology, policy, ethics, and the cultures that grew these compounds. Written by Stephen Page — independent, evidence-led.

Essays

Long-form work

Comprehensive, referenced essays intended to stand as canonical references on their subject. New essays appear rarely; each takes weeks to write.

Endogenous DMT in Humans: A Critical Review of the State of the Evidence

Featured Essay · 54 min read

Endogenous DMT in Humans: A Critical Review of the State of the Evidence

A critical review of the evidence, the inferences drawn from it, and the limits of cross-species extrapolation: detection, biosynthesis, function and psychoactive sufficiency .

May 12, 2026

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