Applied Research Through DMT
Altered Reality · Autonoetic Reflection
Daily Field Notes on emerging psychedelic research, plus long-form essays on pharmacology, policy, ethics, and the cultures that grew these compounds. Written by Stephen Page — independent, evidence-led.
Essays
Long-form work
Comprehensive, referenced essays intended to stand as canonical references on their subject. New essays appear rarely; each takes weeks to write.
Featured Essay · 54 min read
Endogenous DMT in Humans: A Critical Review of the State of the Evidence
A critical review of the evidence, the inferences drawn from it, and the limits of cross-species extrapolation: detection, biosynthesis, function and psychoactive sufficiency .
Read essay →Latest Field Notes
ARDMT Field Notes
Why 0.4 mg/kg: Strassman's dose-finding logic and its thirty-year hold
Strassman's dose-finding study, published in Archives of General Psychiatry in 1994, employed a double-blind design with four intravenous dose levels — 0.05, 0.1, 0.2, and 0.4 mg/kg of DMT fumarate